D-910

Diazepam-d₅ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₁₆D₅H₈ClN₂O
• Número de CAS: 65854-76-4
• Peso molecular: 289.77
• EC Number: 200-659-6
• MDL number: MFCD00070151
• UNSPSC Code: 41116107
• PubChem Substance ID: 329798892
• NACRES: NA.24

Propiedades

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: O=C1CN=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3=C(C=CC(Cl)=C3)N1C
• InChI: 1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3/i2D,3D,4D,5D,6D
• InChI key: AAOVKJBEBIDNHE-VIQYUKPQSA-N

Descripción

General description

Diazepam is a benzodiazepine used to treat a number of symptoms from anxiety and panic attacks to insomnia. This stable-labeled internal standard is suited for quantitation of diazepam levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or isotope dilution methods. Diazepam, a benzodiazpine frequently abused recreationally, is sold under the trade name Valium^®.

Application

• Diazepam-d₅ as an analytical standard: Diazepam-d₅ is widely used as a stable isotope-labeled standard in analytical research for accurate quantification of diazepam in biological samples. It ensures high precision in mass spectrometry analyses, crucial for both therapeutic monitoring and forensic investigations (Wagmann et al., 2020).


• Internal standard in mass spectrometry: As an internal standard, Diazepam-d₅ provides consistency and accuracy in mass spectrometric quantification of drugs, aiding in the robust analysis required in pharmacokinetic studies and drug metabolism research. This application is essential for determining drug concentration and studying metabolic pathways in clinical pharmacology (Villain et al., 2004).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Valium is a registered trademark of Roche Products Inc.

Información de seguridad

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup