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Merck

860924P

Avanti

N-24:0(2R-OH) Phytosphingosine

Avanti Polar Lipids 860924P, powder

Sinónimos:

N-(2′-(R)-hydroxylignoceroyl)-phytosphingosine (Saccharomyces Cerevisiae)

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About This Item

Fórmula empírica (notación de Hill):
C42H85NO5
Número de CAS:
Peso molecular:
684.13
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860924P-10mg)
pkg of 1 × 5 mg (860924P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860924P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC([C@H](O)CCCCCCCCCCCCCCCCCCCCCC)=O)CO

InChI

1S/C42H85NO5/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-40(46)42(48)43-38(37-44)41(47)39(45)35-33-31-29-27-25-16-14-12-10-8-6-4-2/h38-41,44-47H,3-37H2,1-2H3,(H,43,48)

InChI key

ZFUXWVVVWGWGPQ-UHFFFAOYSA-N

General description

N-24:0(2R-OH) Phytosphingosine, also called as N-(2′-(R)-hydroxylignoceroyl)-phytosphingosine, is a sphingolipid that belongs to the group of phytoceramides. Phytosphingosine is a sphingoid base with hydroxyl group at the C4 position. It is highly found in plants and fungi. In addition, phytosphingosine is also present in mammalian epidermis, including the stratum corneum.

Application

N-24:0(2R-OH) Phytosphingosine, also called as N-(2′-(R)-hydroxylignoceroyl)-phytosphingosine may be used to study its effects in different hybrids of Zea mays.

Biochem/physiol Actions

Phytosphingosine and its derivatives play a vital role in the body′s natural defense system. These lipids prevent dehydration of skin, control epidermal cell growth, differentiation and apoptosis. Phytosphingosine also exhibits anti-bactericidal and anti-inflammatory properties.

Packaging

5 mL Amber Glass Screw Cap Vial (860924P-10mg)
5 mL Amber Glass Screw Cap Vial (860924P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

No data available

flash_point_c

No data available


Certificados de análisis (COA)

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Paola Giorni et al.
Toxins, 7(9), 3657-3670 (2015-09-18)
Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions. Host cuticle/cell wall/membrane components such as sphingolipids and oxylipins may contribute to determining
Byung-Hak Kim et al.
The Journal of investigative dermatology, 134(4), 1023-1032 (2013-11-02)
Phytosphingosine is abundant in plants and fungi and is found in mammalian epidermis, including the stratum corneum. Phytosphingosine and its derivatives N-acetyl phytosphingosine and tetraacetyl phytosphingosine are part of the natural defense system of the body. However, these molecules exhibit

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