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860656P

Avanti

Lyso SM (d17:1)

Avanti Research™ - A Croda Brand 860656P, powder

Sinónimos:

Sphingosylphosphorylcholine (C17 base)

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About This Item

Fórmula empírica (notación de Hill):
C22H47N2O5P
Número de CAS:
118540-32-2
Peso molecular:
450.59
MDL number:
MFCD22416606
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860656P-10mg)
pkg of 1 × 5 mg (860656P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860656P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@@]([H])(N)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C22H47N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-22(25)21(23)20-29-30(26,27)28-19-18-24(2,3)4/h16-17,21-22,25H,5-15,18-20,23H2,1-4H3/b17-16+/t21-,22+/m0/s1

InChI key

AAERQLSYRRXFMA-FYBNUODKSA-N

General description

Lyso-sphingomyelin (Lyso SM) (d17:1), is an amphiphilic lysophospholipid with a long-chain sphingosine (C17 base) and a hydrophilic phosphorylcholine. Lyso SM, also known as sphingosylphosphorylcholine (SPC) is a de-acylated form of sphingomyelin, found in blood plasma.

Biochem/physiol Actions

Lyso-sphingomyelin (Lyso SM) is a vital lipid mediator, with an ability to regulate cell proliferation, migration, differentiation, metabolism and apoptosis. It exhibits various functions in cardiovascular system, immune system, central nervous system and skin. Increased concentration of Lyso SM has been observed in few disease states such as atopic dermatitis, Niemann-Pick disease (NPD) and cancer.

Packaging

5 mL Amber Glass Screw Cap Vial (860656P-10mg)
5 mL Amber Glass Screw Cap Vial (860656P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Certificados de análisis (COA)

Lot/Batch Number

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Di Ge et al.
Acta pharmacologica Sinica, 39(12), 1830-1836 (2018-07-28)
Sphingosylphosphorylcholine (SPC) is a bioactive sphingolipid in blood plasma that is metabolized from the hydrolysis of the membrane sphingolipid. SPC maintains low levels in the circulation under normal conditions, which makes studying its origin and action difficult. In recent years

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