860546P

C24:1 Galactosyl(β) Ceramide (d18:1/24:1(15Z))

Avanti Polar Lipids 860546P, powder

• Sinónimos: D-galactosyl-β-1,1′ N-nervonoyl-D-erythro-sphingosine
• Fórmula empírica (notación de Hill): C₄₈H₉₁NO₈
• Número de CAS: 17283-91-9
• Peso molecular: 810.24
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• form: powder
• packaging: pkg of 1 × 5 mg (860546P-5mg)
• manufacturer/tradename: Avanti Polar Lipids 860546P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O
• InChI: 1S/C48H91NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(40-56-48-47(55)46(54)45(53)43(39-50)57-48)42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,41-43,45-48,50-51,53-55H,3-16,19-34,36,38-40H2,1-2H3,(H,49,52)/b18-17-,37-35+/t41?,42-,43-,45+,46+,47-,48+/m1/s1
• InChI key: WBOZIXHPUPAOIA-KVGFKTOYSA-N

Descripción

General description

β-Galactosylceramides (GalCers) or cerebrosides are synthesized from the glycosphingolipids by or β-GalCer synthase. They are localized in cytosolic face cell membrane after synthesis from Golgi and endoplasmic reticulum. GalCers are present in the brain and myelin structures.

Application

C24:1 Galactosyl(β) Ceramide (d18:1/24:1(15Z)) is suitable for use

• as a standard hexosylceramide for hydrophilic interaction chromatography-based liquid chromatography mass spectroscopy
• as a lipid standard in ozone-induced dissociation mass spectrometry
• in lipid nanotubes (LNT) preparation in combination with phosphatidylserine

Biochem/physiol Actions

β-Galactosylceramides (GalCers) levels are elevated in Krabbe′s disease due to the galactosylceramidase enzyme deficiency. High levels of nervonic acid-containing ceramide (d18:1/24:1) is associated with aging.

Packaging

5 mL Amber Glass Screw Cap Vial (860546P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable