855375P

10:0 Lyso PC

1-decanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

• Sinónimos: 1-decanoyl-sn-glycero-3-phosphocholine; PC(10:0/0:0)
• Fórmula empírica (notación de Hill): C₁₈H₃₈NO₇P
• Número de CAS: 22248-63-1
• Peso molecular: 411.47
• UNSPSC Code: 51191904
• NACRES: NA.25

Propiedades

• assay: >99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
• form: powder
• packaging: pkg of 1 × 25 mg (855375P-25mg); pkg of 1 × 500 mg (855375P-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 855375P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCC)=O
• InChI: 1S/C18H38NO7P/c1-5-6-7-8-9-10-11-12-18(21)24-15-17(20)16-26-27(22,23)25-14-13-19(2,3)4/h17,20H,5-16H2,1-4H3/t17-/m1/s1
• InChI key: SECPDKKEUKDCPG-QGZVFWFLSA-N

Descripción

General description

Lyso-phosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response. It has a choline group at its polar head.

Application

10:0 Lyso PC has been used as an internal standard to quantify the most abundant lysophosphatidylcholine (LPC) species found in Trypanosoma cruzi samples.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) alters various biological functions in different cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.

Packaging

20 mL Clear Glass Screw Cap Vial (855375P-500mg)

5 mL Clear Glass Sealed Ampule (855375P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable