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Merck

850303P

Avanti

04:0 PC

1,2-dibutyryl-sn-glycero-3-phosphocholine, powder

Sinónimos:

PC(4:0/4:0)

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About This Item

Fórmula empírica (notación de Hill):
C16H32NO8P
Número de CAS:
Peso molecular:
397.40
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850303P-25mg)
pkg of 1 × 500 mg (850303P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850303P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COC(CCC)=O)=O

InChI

1S/C16H32NO8P/c1-6-8-15(18)22-12-14(25-16(19)9-7-2)13-24-26(20,21)23-11-10-17(3,4)5/h14H,6-13H2,1-5H3/t14-/m1/s1

InChI key

QIJYAMAPPUXBSC-CQSZACIVSA-N

General description

04:0 PC is a water soluble phophatidylcholine analogue. Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

04:0 PC is suitable for use to evaluate its ability to form reverse micelles. It is also suitable for use as a phospholipid substrate to study the substrate specificity of glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP).

Biochem/physiol Actions

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Packaging

30 mL Amber Wide Mouth Bottle with Screw Cap (850303P-500mg)
5 mL Clear Glass Sealed Ampule (850303P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Role of reverse micelles on lipid oxidation in bulk oils: impact of phospholipids on antioxidant activity of alpha-tocopherol and Trolox
Chen B, et al.
Food & Function, 2(6), 302-309 (2011)
The Membranes of Cells (2016)
Characterization of glycerophosphoethanolamine ethanolaminephosphodiesterase from Streptomyces sanglieri
Mineta S, et al.
Journal of Bioscience and Bioengineering, 119(2), 123-130 (2015)
Mi-Kyung Oh et al.
Biochimica et biophysica acta, 1649(2), 146-153 (2003-07-25)
O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates (n=6, 8, and 10; CnPNC) were synthesized and characterized as inhibitors of phospholipase D (PLD) activity toward phosphatidylcholine presented as monomers, micelles, and bilayers. Detailed studies with recombinant Streptomyces chromofuscus PLD, a Ca(2+)-activated enzyme that does not show large
Integrative Medicine - E-Book (2017)

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