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850187P

Avanti

08:0 PI(3)P

1,2-dioctanoyl-sn-glycero-3-(phosphoinositol-3-phosphate) (ammonium salt), powder

Sinónimos:

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′-phosphate) (ammonium salt); PIP[3′](8:0/8:0)

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About This Item

Fórmula empírica (notación de Hill):
C25H54N2O16P2
Número de CAS:
299216-98-1
Peso molecular:
700.65
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850187P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850187P-500ug))

manufacturer/tradename

Avanti Research™ - A Croda Brand 850187P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+]

General description

Phosphatidylinositol 3-monophosphate (PI3P) is a lipid, found abundantly in eukaryotic cells. It is also present at low level in mammalian cells.

Application

08:0 PI(3)P has been used in the preparation of model membrane for protein reconstitution and structural studies.

Biochem/physiol Actions

Phosphatidylinositol 3-monophosphate (PI3P) participates in vesicular trafficking processes. It also plays a key role in endocytosis.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850187P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850187P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

No data available

flash_point_c

No data available

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Structural and functional studies of membrane remodeling machines
Methods in Cell Biology, 128, 165-200 (2015)
Lina Tawk et al.
Eukaryotic cell, 9(10), 1519-1530 (2010-08-17)
Phosphoinositides are important regulators of diverse cellular functions, and phosphatidylinositol 3-monophosphate (PI3P) is a key element in vesicular trafficking processes. During its intraerythrocytic development, the malaria parasite Plasmodium falciparum establishes a sophisticated but poorly characterized protein and lipid trafficking system.
Etienne Morel et al.
Nature communications, 4, 2250-2250 (2013-08-03)
Defects in endosomal sorting have been implicated in Alzheimer's disease. Endosomal traffic is largely controlled by phosphatidylinositol-3-phosphate, a phosphoinositide synthesized primarily by lipid kinase Vps34. Here we show that phosphatidylinositol-3-phosphate is selectively deficient in brain tissue from humans with Alzheimer's

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