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Merck

850181P

Avanti

08:0 PI

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Sinónimos:

PI(8:0/8:0)

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About This Item

Fórmula empírica (notación de Hill):
C25H50NO13P
Número de CAS:
Peso molecular:
603.64
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850181P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850181P-500ug))

manufacturer/tradename

Avanti Polar Lipids 850181P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+]

General description

Phosphatidylinositol (PI), a glycerophospholipid has a head group which carries a cyclohexanol moiety. 08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) is a PI analog with a shorter acyl chain.

Application

08:0 PI (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol)) may be used:
  • as a substrate for phosphatidyl-myo-inositol mannosyltransferase (PimA) to compare the effect of non-substrate phospholipids on the activity
  • as a replacement for mycobacterial membranes in enzymatic assays to measure PimA activity
  • as a phospholipid (PL) standard in the ion trap-time of flight (IT-TOF) system to study the fragmentation principles of unique PLs and also used as a nonendogenous PL standard for the quantitative analysis of PLs in nut samples

Biochem/physiol Actions

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol (PI) serves as a precursor of a phosphoinositides, a class of signaling lipids.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850181P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available


Certificados de análisis (COA)

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Zhen Chen et al.
Theriogenology, 144, 56-66 (2020-01-10)
A comparative lipidomic profiling analysis of dairy cattle oocytes with different developmental competences was performed using a combination of high performance liquid chromatography-high resolution tandem mass spectrometry and multivariate statistical analysis. Significant lipidomic changes were identified in degenerating oocytes. Total
Shuang Song et al.
Food chemistry, 240, 1171-1178 (2017-09-28)
Nuts, a class of fatty natural food, are associated with a series of health benefit. Lipid, which is the most abundant nutrient in nuts, could be one of the major contributors to many beneficial effects. In previous studies, only the

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