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Merck

850100P

Avanti

18:1 Lyso PI

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Sinónimos:

1-(9Z-octadecenoyl)-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt); PI(18:1(9Z)/0:0); 110720

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About This Item

Fórmula empírica (notación de Hill):
C27H54NO12P
Número de CAS:
Peso molecular:
615.69
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850100P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850100P-500ug))

manufacturer/tradename

Avanti Research - A Croda Brand 850100P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

Categorías relacionadas

General description

Phosphatidylinositol (PtdIns) is a structural phospholipid. PI is synthesized by mycobacteria and other bacterial genera in prokaryotes.

Application

18:1 Lyso PI is suitable for use to quantify the fatty acids, lysophospholipids (LPLs), and phospholipids (PLs) and LPAs in gintonin-enriched fraction (GEF) by liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Biochem/physiol Actions

Phosphatidylinositol (PI) participates in polyphosphoinositide turnover. It can be used as a substrate to produce several molecules, that can modulate various cellular functions. In eukaryotes, phosphatidylinositol (PI)-based lipids (phosphoinositides) plays a key role in intracellular signalling. It is also involved in the anchoring of glycosylphosphatidylinositol-linked proteins to the membrane.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850100P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850100P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Phosphatidylinositol 4-Kinase from Bovine Brain
Methods in Neurosciences, 18, 93-99 (1993)
Phosphatidylinositol Turnover and Receptors
reference module in biomedical sciences (2016)
Bioactive lipids in gintonin-enriched fraction from ginseng
Cho HJ, et al.
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Structural basis for phosphatidylinositol-phosphate biosynthesis
Clarke OB, et al.
Nature Communications, 6, 8505-8505 (2015)
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Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple

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