810283P
Avanti
TopFluor® PS
Avanti Polar Lipids 810283P, powder
Sinónimos:
1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phospho-L-serine (ammonium salt)
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About This Item
Fórmula empírica (notación de Hill):
C46H80BF2N4O10P
Número de CAS:
Peso molecular:
928.93
UNSPSC Code:
12352211
NACRES:
NA.25
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assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810283P-1mg)
manufacturer/tradename
Avanti Polar Lipids 810283P
shipped in
dry ice
storage temp.
−20°C
Categorías relacionadas
General description
TopFluor®, a fluorescent molecule carries dipyrromethene boron difluoride moiety. It is linked to several lipid molecules by means of covalent attachment. Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.
Application
TopFluor® PS may be used in liposome generation and as a synthetic fluorescent phosphoserine (PS) analogue to study PS distribution and dynamics in mouse embryonic fibroblasts (MEFs). It has also been used in the preparation of donor liposomes.
Biochem/physiol Actions
Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. PS actively participates in the locomotor functions, like rapid reactions and reflexes.
Packaging
5 mL Amber Glass Screw Cap Vial (810283P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies
Conrad KS, et al.
Nature Communications, 8(1908), 1-13 (2017)
Phosphatidylserine dynamics in cellular membranes
Kay JG, et al.
Molecular Biology of the Cell, 23(11), 2198-2212 (2012)
Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease
Hernandez-Alvarez MI, et al.
Cell, 177(4), 881-895 (2019)
Adsorption of O-phospho-L-serine and L-serine onto poorly crystalline apatite
Benaziz L, et al.
Journal of Colloid and Interface Science, 238(1), 48-53 (2001)
Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate
Shirey CM, et al.
Chemistry and Physics of Lipids, 200, 32-32 (2016)
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