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Key Documents

700066P

Avanti

7-dehydrocholesterol

Δ,5,7-cholesterol, powder

Sinónimos:

7-dehydrocholesterin; Provitamin D3; 110807

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About This Item

Fórmula empírica (notación de Hill):
C27H44O
Número de CAS:
Peso molecular:
384.64
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (700066P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 700066P

shipped in

dry ice

storage temp.

−70°C

InChI

1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3

InChI key

UCTLRSWJYQTBFZ-UHFFFAOYSA-N

General description

7-dehydrocholesterol is a metabolite produced in cholesterol synthesis. It is an unsaturated sterol predominantly found in the epidermis.

Application

7-dehydrocholesterol has been used:
  • in gas chromatography/mass spectrometry (GC/MS)-based sterol profiling to quantify 7-dehydrocholesterol in oligodendrocyte progenitor cells (OPCs)
  • as an internal standard for the analysis of sterols and oxysterols using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • as an internal standard for lipid measurements by liquid chromatography (LC)-MS

Biochem/physiol Actions

7-dehydrocholesterol acts as a precursor of vitamin D3 under the conditions of high temperature and ultraviolet (UV) light.

Packaging

5 mL Amber Glass Screw Cap Vial (700066P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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7-Dehydrocholesterol, an immediate metabolic predecessor of cholesterol, can accumulate in tissues due to some metabolic abnormalities, causing an array of symptoms known as Smith-Lemli-Opitz syndrome. Enrichment of cellular membranes with 7-dehydrocholesterol interferes with normal cell-signaling processes, which involve interaction between
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