700057P

22(S)-hydroxycholesterol

Avanti Research^™ - A Croda Brand

• Sinónimos: 5-cholestene-3β,22-diol; 22-hydroxycholest-5-en-3-ol
• Fórmula empírica (notación de Hill): C₂₇H₄₆O₂
• Número de CAS: 22348-64-7
• Peso molecular: 402.65
• MDL number: MFCD00010476
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• description: cholest-5-ene-3β,22(S)-diol
• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 5 mg (700057P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H]([C@@H](O)CCC(C)C)C)(CC3)C)CC=C2C1)C
• InChI: 1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25-,26-,27+/m0/s1
• InChI key: RZPAXNJLEKLXNO-QUOSNDFLSA-N

Descripción

General description

22(S)-hydroxycholesterol is a stereo isoform of the 22(R)-hydroxycholesterol.

Biochem/physiol Actions

22(S)-hydroxycholesterol (22(S)-HC) promotes glucose catabolism and uptake. It is regarded as a potential target to treat type 2 diabetes. 22(S)-HC also prevents the accumulation of lipids and lipid synthesis in hepatocytes and myotubes. It shows no interaction with liver X receptor (LXR) like 22(R)-hydroxycholesterol and is not estrogenic.

Packaging

5 mL Amber Glass Screw Cap Vial (700057P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable