699854P

4A-MPLA (isomer C3)

Avanti Research^™ - A Croda Brand

• Sinónimos: Monophosphopdyl Tetra-acyl Lipid A
• Fórmula empírica (notación de Hill): C₆₈H₁₃₂N₃O₁₉P
• Número de CAS: 2260669-09-6
• Peso molecular: 1326.76
• UNSPSC Code: 12352211
• NACRES: NA.25

Propiedades

• assay: >99% (HPLC)
• form: powder
• packaging: pkg of 1 × 1 mg (699854P-1mg); pkg of 1 × 5 mg (699854P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• application(s): vaccine development
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@H]([C@@H](CO[C@@H]([C@@H]1NC(C[C@H](OC(CCCCCCCCCCCCC)=O)CCCCCCCCCCC)=O)O[C@H](CO)[C@@H](OP([O-])(O)=O)[C@@H]1O)O[C@H](O)[C@@H]2NC(C[C@H](O)CCCCCCCCCCC)=O)[C@@H]2OC(C[C@H](O)CCCCCCCCCCC)=O.[NH4+]

Descripción

Biochem/physiol Actions

Structural modification of diphosphoryl lipid A by hydrolysis produces MPLA (monophosphoryl lipid A) and is known to decrease its toxicity. MPLA, a lipopolysaccharide derivative, acts an immunomodulator and is non-toxic. For this reason, it is useful as a vaccine adjuvant. The MPLA induced immune response is tissue specific. It enhances host′s resistance against endotoxin induced effects. It also decreases cytokine production during infection.

Packaging

2 mL Amber Glass Crimp Cap Vial (699854P-1mg)

2 mL Amber Glass Crimp Cap Vial (699854P-5mg)

Other Notes

For R&D use only. Not for drug, household, or other uses.

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3