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Merck
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Documentos

A45807

Sigma-Aldrich

2-Amino-5-chlorobenzoxazole

97%

Sinónimos:

Zoxazolamine

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About This Item

Fórmula empírica (notación de Hill):
C7H5ClN2O
Número de CAS:
61-80-3
Peso molecular:
168.58
EC Number:
200-519-4
MDL number:
MFCD00005770
UNSPSC Code:
12352100
PubChem Substance ID:
24890884
NACRES:
NA.22

assay

97%

form

powder

mp

181-184 °C (lit.)

SMILES string

Nc1nc2cc(Cl)ccc2o1

InChI

1S/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)

InChI key

YGCODSQDUUUKIV-UHFFFAOYSA-N

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Yuzhi Jia et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(35), 12531-12536 (2005-08-20)
Peroxisome proliferator-activated receptor-binding protein (PBP), also known as thyroid hormone receptor-associated protein 220/vitamin D receptor-interacting protein 205/mediator 1, an anchor for multisubunit mediator transcription complex, functions as a transcription coactivator for nuclear receptors. Disruption of the PBP gene results in
Junichiro Saito et al.
Phytotherapy research : PTR, 23(7), 901-905 (2009-01-14)
Magnolol has been reported to strongly inhibit the mutagenicity induced by indirect mutagens in the Ames test as well as the clastogenicity induced by benzo(a)pyrene (B(a)P) in the mice micronucleus test. Here, we evaluated the inhibitory effect of magnolol on
I Andreadou et al.
European journal of drug metabolism and pharmacokinetics, 28(1), 7-10 (2003-09-25)
The influence of four ethanolamine derivatives with anti-inflammatory and antioxidant activity on the in vitro aminopyrine N-demethylation was studied. It was found that these compounds inhibit the N-demethylation of aminopyrine. 1-Cyclohexyl-5-(2-hydroxy-ethylamino)-pentan-2-one (compound 4), possessing the highest inhibitory activity and found
Anjana G Vij et al.
The Indian journal of medical research, 135, 211-216 (2012-03-27)
People travelling to high altitude for occupational, recreational or religious purposes are mostly healthy and fit but sometimes they use drugs for common ailments like influenza, acute mountain sickness or chronic disease like diabetes. Limitation of oxygen at high altitude
Romi Ghose et al.
Life sciences, 89(1-2), 57-64 (2011-05-31)
Our aim is to investigate the molecular mechanism of regulation of gene expression of drug metabolizing enzymes (DMEs) and transporters in diet-induced obesity. Adult male CD1 mice were fed diets containing 60% kcal fat (HFD) or 10% kcal fat (LFD)
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