930024
Hyaluronic acid adipic dihydrazide (HA-ADH)
Sinónimos:
HA-ADH
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About This Item
Fórmula lineal:
(C20H33N5O12)n
UNSPSC Code:
12352125
NACRES:
NA.23
Productos recomendados
form
solid (Chunks)
Quality Level
color
white to off-white
application(s)
3D bioprinting
storage temp.
2-8°C
Categorías relacionadas
General description
Adipic acid dihydrazide is commonly used as a functional group to allow for HA cross-linking to polymers containing aldehyde groups or that are aldehyde-functionalized, like HA-aldehyde or PEG-aldehyde. These biomaterials are attractive for their tunable properties and low cytotoxicity.
Degree of functionalization (50-80%)
Application
Hyaluronic acid (HA) is a ubiquitous extracellular matrix component, which makes it attractive for use in medical applications for it′s biocompatibility and low immunogenicity. HA-based polymers are used to make hydrogels for a wide variety of applications from tissue engineering and regeneration to drug delivery and bioinks for 3D bioprinting. To make hydrogels, HA has to be derivatized with groups that can cross-link to to other functionalized polymers.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering
Chen, et al.
Carbohydrate Polymers, 166, 31-44 (2017)
Yuguo Lei et al.
Biomaterials, 32(1), 39-47 (2010-10-12)
Synthetic hydrogel scaffolds that can be used as culture systems that mimic the natural stem cell niche are of increased importance for stem cell biology and regenerative medicine. These artificial niches can be utilized to control the stem cell fate
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