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791342

Sigma-Aldrich

Silica, nanoparticle dispersion in water

<50 nm (DLS), triethoxylpropylaminosilane functionalized

Sinónimos:

NH2 functionalized NPs

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About This Item

UNSPSC Code:
12352302
NACRES:
NA.23

Quality Level

100

form

dispersion
nanoparticles

shelf life

1 yr

concentration

in water (Dispersion)

particle size

<50 nm (DLS)

functional group

amine

storage temp.

20-25°C

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General description

Composition of nanoparticles non-crystalline colloidal SiO2 particles
Dispersion loading and medium (27 ± 3) wt.-% in water
Particle size d90 (volume distribution; DLS) < 50 nm
pH 2 ± 1
Density (1.2 ± 0.1) g/l
Primary particle size < 20 nm
Surface modification using Triethoxylpropylaminosilane

Application

Silica nanoparticles play a crucial role in biotechnology including bone engineering and drug delivery. The amino functionality present on the surface of these materials provide a synthetic handle for further modification and conjugation to target moieties. Amino functionalized silica particles can be used for applicaitons including in vivo gene delivery, nanocomposite formation, and formation of biofilms.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8B - Non-combustible, corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Indrajit Roy et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(2), 279-284 (2005-01-05)
This article reports a multidisciplinary approach to produce fluorescently labeled organically modified silica nanoparticles as a nonviral vector for gene delivery and biophotonics methods to optically monitor intracellular trafficking and gene transfection. Highly monodispersed, stable aqueous suspensions of organically modified
Kazuki Murai et al.
Physical chemistry chemical physics : PCCP, 15(27), 11454-11460 (2013-06-12)
We investigated the drug releasing behavior of a novel nanocarrier system, utilizing a peptide to act as a nanogate to the mesopore, on a mesoporous silica nanoparticle. The surface peptide on mesoporous silica displayed pH-dependant mesopore cap-uncap switching behavior, enabled
Dhruba J Bharali et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(32), 11539-11544 (2005-07-30)
This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as a nonviral vector for efficient in vivo gene delivery. Highly monodispersed, stable aqueous suspension of nanoparticles, surface-functionalized with amino groups for binding of DNA, were prepared and
Pingli He et al.
Langmuir : the ACS journal of surfaces and colloids, 20(3), 722-729 (2005-03-19)
Heme protein hemoglobin (Hb) or myoglobin (Mb) and silica nanoparticles in a variety of charge states were assembled layer-by-layer into films on solid surfaces to investigate the driving forces for film assembly. Cyclic voltammetry (CV), quartz crystal microbalance (QCM), X-ray
Preparation and characterization of epoxy composites filled with functionalized nanosilica particles obtained via sol-gel process
Kang, S..;
Polymer, 42(3), 879-887 (2000)
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