76763
1-(4-Pyridyl)piperazine
≥97.0% (GC)
Sinónimos:
4-Piperazinopyridine
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About This Item
Fórmula empírica (notación de Hill):
C9H13N3
Número de CAS:
Peso molecular:
163.22
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Productos recomendados
Quality Level
assay
≥97.0% (GC)
form
powder
impurities
≤1% water
mp
137-141 °C
SMILES string
C1CN(CCN1)c2ccncc2
InChI
1S/C9H13N3/c1-3-10-4-2-9(1)12-7-5-11-6-8-12/h1-4,11H,5-8H2
InChI key
OQZBAQXTXNIPRA-UHFFFAOYSA-N
Gene Information
rat ... Chrnb2(54239)
Categorías relacionadas
General description
1-(4-Pyridyl) piperazine (or 4-Piperazinopyridine) is an active structural component that is used as a building block to prepare various medicinally important active molecules.
Application
1-(4-Pyridyl) piperazine can be used as a building block for the synthesis of:
- Nocathiacin I analogs for antibacterial studies.
- 4-amino-pyridyl derivatives, benzimido isoquinoline based derivatives and tert-pentylphenoxyalkyl piperazine derivatives for various biological applications.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Benzimidazo [2, 1-a] benz [de] isoquinoline-7-one-12-carboxylic acid based fluorescent sensors for pH and Fe3+
Zhao Y, et al.
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Synthesis, characterization, and bioactivity of new bisamidrazone derivatives as possible anticancer agents.
Al-Qtaitat M A, et al.
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N ε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure?Activity Relationships, and Pharmacokinetic Profiling.
Wodtke R, et al.
Journal of Medicinal Chemistry, 61(10), 4528-4560 (2018)
Identification of ML204: a novel potent antagonist that selectively modulates native TRPC4/C5 channels.
Miller M, et al.
The Journal of Biological Chemistry, jbc-M111 (2011)
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