637513

(S)-(+)-3-Fluoropyrrolidine hydrochloride

97%

• Sinónimos: (3S)-(+)-3-Fluoropyrrolidine hydrochloride, (3S)-3-Fluoropyrrolidine hydrochloride
• Fórmula empírica (notación de Hill): C₄H₈FN · HCl
• Número de CAS: 136725-53-6
• Peso molecular: 125.57
• MDL number: MFCD04038718
• UNSPSC Code: 12352005
• PubChem Substance ID: 24882861
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 97%
• form: solid
• optical activity: [α]20/D +8°, c = 1% in methanol
• mp: 183-187 °C (lit.)
• SMILES string: Cl.F[C@H]1CCNC1
• InChI: 1S/C4H8FN.ClH/c5-4-1-2-6-3-4;/h4,6H,1-3H2;1H/t4-;/m0./s1
• InChI key: LENYOXXELREKGZ-WCCKRBBISA-N

Descripción

Application

(S)-(+)-3-Fluoropyrrolidine hydrochloride can be employed as a building block for the preparation of:

• Fluorinated pyrrolidine derivatives of cyclohexylglycine amides as potential inhibitors for dipeptidyl peptidase IV.
• Fluoropyrrolidine contaning N--ethylurea pyrazole derivatives as potential and selective inhibitors for Trypanosoma brucei and Trypanosoma cruzi parasitic causative agents.
• Urea derivatives of (S)-2-(3,4-difluorophenyl)-5-(3-fluoro-N-pyrrolidylamido)benzothiazole as potent antitrypanosomal agents.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 - H315 - H319 - H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves