55452
D-α-Hydroxyisovaleric acid
≥98.0% (T)
Sinónimos:
(R)-2-Hydroxy-3-methylbutyric acid
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About This Item
Productos recomendados
assay
≥98.0% (T)
form
solid
optical activity
[α]20/D −17±1°, c = 1% in chloroform
mp
64-67 °C
functional group
carboxylic acid
hydroxyl
SMILES string
CC(C)[C@@H](O)C(O)=O
InChI
1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/t4-/m1/s1
InChI key
NGEWQZIDQIYUNV-SCSAIBSYSA-N
Application
D-α-Hydroxyisovaleric acid may be used in the preparation of biodegradable, optically active and isotactic poly(D-2-hydroxy-3-methylbutanoic acid).
Other Notes
This chiral α-hydroxy acid is used for the synthesis of peptides and depsipeptides. It is further used as chiral building block. Synthesis of α-substituted α-hydroxy acids via dioxolanone intermediates.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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A rapid dried-filter paper plasma-spot analytical method was developed to quantify organic acids, amino acids, and glycines simultaneously in a two-step derivatization procedure with good sensitivity and specificity. The new method involves a two-step trimethylsilyl (TMS) - trifluoroacyl (TFA) derivatization
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