511943
1-Acetyl-4-(4-hydroxyphenyl)piperazine
98%
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About This Item
Fórmula empírica (notación de Hill):
C12H16N2O2
Número de CAS:
Peso molecular:
220.27
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
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assay
98%
mp
180-185 °C (lit.)
SMILES string
CC(=O)N1CCN(CC1)c2ccc(O)cc2
InChI
1S/C12H16N2O2/c1-10(15)13-6-8-14(9-7-13)11-2-4-12(16)5-3-11/h2-5,16H,6-9H2,1H3
InChI key
AGVNLFCRZULMKK-UHFFFAOYSA-N
General description
1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP), a piperazine derivative, is a structural analog of acetaminophen. Its multi-step preparation using bis-(2-chloroethyl)amine hydrochloride and p-aminophenol as starting materials has been reported.2
Application
1-Acetyl-4-(4-hydroxyphenyl)piperazine may be used in the preparation of 1-acetyl-4-(4-octadecyloxyphenyl)piperazine. It may also be used in the multi-step synthesis of ketoconazole, its 1,2,4-triazole and thiazole analogs.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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