467464
Thianaphthene-2-carboxylic acid
98%
Sinónimos:
Benzo[b]thiophene-2-carboxylic acid
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About This Item
Fórmula empírica (notación de Hill):
C9H6O2S
Número de CAS:
Peso molecular:
178.21
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
98%
mp
241-244 °C (lit.)
SMILES string
OC(=O)c1cc2ccccc2s1
InChI
1S/C9H6O2S/c10-9(11)8-5-6-3-1-2-4-7(6)12-8/h1-5H,(H,10,11)
InChI key
DYSJMQABFPKAQM-UHFFFAOYSA-N
General description
Thianaphthene-2-carboxylic acid, a benzothiophene, is a heterocyclic sulfur compound. It undergoes degradation (23%) by employing a mixture of washed cells of Rhodococcus erythropolis DS-3 and Gordonia sp. C-6.
Application
Thianaphthene-2-carboxylic acid may be used for the fabrication of carboxylated conducting polymer/CNTs (carbon nanotubes) composites thin films.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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J C Robin et al.
Calcified tissue international, 36(2), 194-199 (1984-03-01)
The purpose of the present study was to investigate the mechanism of action on bone of Benzo(B)Thiophene-2-Carboxylic Acid (BL-5583). BL-5583, at a dose range of 0.01-100 micrograms/ml, inhibited spontaneous as well as A23187 and PTH-induced bone resorption in tissue culture.
J C Robin et al.
Journal of medicine, 11(1), 15-27 (1980-01-01)
Total skeletal calcium was determined in female mice with the aid of whole body neutron activation analysis. Three months treatment with heaprin produced significant osteoporosis in C3-H/St(Ha) mice but not in C57/BL6(J) mice. This was more pronounced in the younger
The synthesis of some substituted thianaphthene-2-carboxamides and their antifungal properties.
Goettsch RW and Wiese GA.
Journal of the American Pharmaceutical Association, 47(5), 319-322 (1958)
Fabrication of Carboxylated Conducting Polymer/CNTs Composites Thin Films for Immunosensor Application.
Netsuwan P, et al.
Mol. Cryst. Liq. Cryst., 580(1), 7-14 (2013)
M Nyska et al.
International journal of experimental pathology, 73(6), 733-740 (1992-12-01)
Thionaphthene-2-carboxylic acid (TNCA) has been shown to decrease osteoclast-mediated bone resorption in vitro and has shown efficacy in animal models of hypercalcaemia of malignancy. In this study, the effects of TNCA on the tibial proximal epiphysis and the sternum have
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