425761

4-tert-Butylphenol

purified by sublimation, 99%

• Fórmula lineal: (CH₃)₃CC₆H₄OH
• Número de CAS: 98-54-4
• Peso molecular: 150.22
• Beilstein/REAXYS Number: 1817334
• EC Number: 202-679-0
• MDL number: MFCD00002367
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866665
• NACRES: NA.22

Propiedades

• vapor pressure: 1 mmHg ( 70 °C)
• assay: 99%
• purified by: sublimation
• bp: 236-238 °C (lit.)
• mp: 96-101 °C (lit.)
• density: 0.908 g/mL at 25 °C (lit.)
• SMILES string: CC(C)(C)c1ccc(O)cc1
• InChI: 1S/C10H14O/c1-10(2,3)8-4-6-9(11)7-5-8/h4-7,11H,1-3H3
• InChI key: QHPQWRBYOIRBIT-UHFFFAOYSA-N
• Gene Information: mouse ... Esr1(13982) ; rat ... Ar(24208)

Descripción

General description

4-tert-Butylphenol (t-BP, 4-TBP, p-tert-butylphenol, PTBP) is an alkyl phenol. It is an aquatic pollutant and an endocrine disrupting chemical (EDC). Exposure to 4-TBP is reported to be one of the factors causing vitiligo. Its genotoxic potential has been studied by in vivo micronucleus tests in a category approach. The degradation of t-BP in water using UV/micro-aeration process has been investigated. Methods for its determination in water and cereal samples have been reported. The kinetics of chlorination reaction of 4-tert-butylphenol in aqua has been studied. The hydrogenation of PTBP to form cis-4-tert-butylcyclohexanol (PTBCH) with high selectivity in the presence of supported rhodium catalyst has been reported. The effect of UV and combined MW–UV irradiation on 4-TBP transformation has been studied.

Application

4-tert-Butylphenol may be used as a sole carbon source for Sphingobium fuliginis strains isolated from rhizosphere sediment of the reed Phragmites australis. It may be used as a precursor to synthesize 4-fluorophenols.

Información de seguridad

• pictograms: GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H315,H318,H361f,H410
• pcodes: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves