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Merck

404624

Sigma-Aldrich

3-Aminopyrrolidine dihydrochloride

98%

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About This Item

Fórmula empírica (notación de Hill):
C4H10N2 · 2HCl
Número de CAS:
Peso molecular:
159.06
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

form

solid

mp

>300 °C (lit.)

SMILES string

Cl[H].Cl[H].NC1CCNC1

InChI

1S/C4H10N2.2ClH/c5-4-1-2-6-3-4;;/h4,6H,1-3,5H2;2*1H

InChI key

NJPNCMOUEXEGBL-UHFFFAOYSA-N

General description

3-Aminopyrrolidine dihydrochloride (3-pyrrolidinamine dihydrochloride) is one of the key intermediate of tosufloxacin and other quinolone antibiotics.

Application

3-Aminopyrrolidine dihydrochloride is the suitable reagent used as an internal standard for the quantitative analysis of amino acids in bio-fluids. (R,S) 3-Aminopyrrolidine dihydrochloride may be used in the preparation of cis-[PdCl2(pyrr)] and cis-[PtCl2(pyrr)] (pyrr= (R,S)-3-aminopyrrolidine) complexes.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Synthesis of 3-Aminopyrrolidine and its N-alkylating Derivatives [J].
Run-pu SHEN, et al.
Journal of Chemical Engineering of Chinese Universities / Gao Xiao Hua Xue Gong Cheng Xue Bao, 4, 014-014 (2003)
Pd (II) and Pt (II)(R, S)-3-aminopyrrolidine complexes. Reactions with 9-ethylguanine and study of their antiproliferative activity.
Riera X, et al.
Inorgorganica Chimica Acta, 339, 253-264 (2002)
Jieyu Zhao et al.
Journal of proteome research, 15(2), 468-476 (2016-01-20)
The interaction between carbon (C) and nitrogen (N) metabolism can reflect plant growth status and environmental factors. Little is known regarding the connections between C-N metabolism and growing regions under field conditions. To comprehensively investigate the relationship in mature tobacco
Shahlizah Sahul Hamid et al.
Planta, 249(6), 1921-1947 (2019-03-21)
Among seaweed groups, brown algae had characteristically high concentrations of mannitol, and green algae were characterised by fructose. In red algae, metabolite profiles of individual species should be evaluated. Seaweeds are metabolically different from terrestrial plants. However, general metabolite profiles
Shuxin Liu et al.
Scientific reports, 7(1), 8150-8150 (2017-08-16)
Uremia has been a rapidly increasing health problem in China. Hemodialysis (HD) is the main renal replacement therapy for uremia. The results of large-scale clinical trials have shown that the HD pattern is crucial for long-term prognosis of maintenance hemodialysis

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