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295906

Sigma-Aldrich

Poli(etilenglicol)

average Mn 2,050, chips

Sinónimos:

PEG

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About This Item

Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24857821
NACRES:
NA.23

product name

Poli(etilenglicol), average Mn 2,050, chips

form

chips

mol wt

average Mn 2,050

mp

52-54 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application

  • Cytotoxicity Study of Polyethylene Glycol Derivatives: Evaluates the cytotoxic effects of various PEG derivatives, important for chemists in pharmaceutical development and safety assessment (Liu et al., 2017).
  • ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles: Introduces a PEG-based method for isolating exosomes, useful for researchers in biomedical and clinical sciences (Rider et al., 2016).

Other Notes

Molecular weight: Mn 1,900-2,200

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCH0926
BCCH0927
BCCG4863
BCCG4858
BCCF9450

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Poli(etilenglicol) average Mn 600, waxy solid (moist)

Sigma-Aldrich

202401

Poli(etilenglicol)

Poli(etilenglicol) average mol wt 10,000

Sigma-Aldrich

P6667

Poli(etilenglicol)

Poli(etilenglicol) Mr ~1500, pkg of 10 × 4 mL, solution

Roche

10783641001

Poli(etilenglicol)

Poli(etilenglicol) average Mv ~8,000, powder (crystalline)

Sigma-Aldrich

202452

Poli(etilenglicol)

Chenlu Zhang et al.
PloS one, 12(9), e0184730-e0184730 (2017-09-09)
The economic production of cellulosic biofuel requires efficient and full utilization of all abundant carbohydrates naturally released from plant biomass by enzyme cocktails. Recently, we reconstituted the Neurospora crassa xylodextrin transport and consumption system in Saccharomyces cerevisiae, enabling growth of
Paras R Patel et al.
Journal of neural engineering, 12(4), 046009-046009 (2015-06-03)
Single carbon fiber electrodes (d = 8.4 μm) insulated with parylene-c and functionalized with pTS have been shown to record single unit activity but manual implantation of these devices with forceps can be difficult. Without an improvement in the insertion
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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