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Merck

274135

Sigma-Aldrich

N,N-Dimethylacrylamide

99%, contains 500 ppm monomethyl ether hydroquinone as inhibitor

Sinónimos:

2-Propenamide

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About This Item

Fórmula lineal:
CH2=CHCON(CH3)2
Número de CAS:
Peso molecular:
99.13
Beilstein/REAXYS Number:
1742219
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

99%

form

liquid

contains

500 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.473 (lit.)

bp

80-81 °C/20 mmHg (lit.)

density

0.962 g/mL at 25 °C (lit.)

SMILES string

CN(C)C(=O)C=C

InChI

1S/C5H9NO/c1-4-5(7)6(2)3/h4H,1H2,2-3H3

InChI key

YLGYACDQVQQZSW-UHFFFAOYSA-N

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General description

N,N-Dimethylacrylamide (DMAA) is a non-ionic monomer with high reactivity and low initiation temperature. It is commonly used as a monomer in the production of polymers and copolymers for various applications such as hydrogels, polymeric flocculants, biomedical and drug delivery applications, polymer coatings, smart coatings, adhesives, sensors, self-healing materials, and water treatment agents. The unique structure of DMMA can form a three-dimensional network with other hydrogels and enhance their water retention capacity. It is also used as a crosslinking agent in polymerization reactions.

Application

N, N-Dimethylacrylamide(DMAA) can be used in the following applications:
  • Synthesis of poly(N,N-dimethylacrylamide) (PDMAA) nanoparticles which are used in biomedical and drug delivery applications.
  • Use as a co-monomer in the synthesis of thermoresponsive polymers used in smart coatings, adhesives, and sensors.
  • As a reactive diluent in the manufacture of UV-cured coatings and inks.
  • Use as a co-monomer with polyethylene glycol dimethacrylate (PEGDMA) and a chitosan derivative to develop an injectable hydrogel that can be used as a bone tissue engineering matrix.
  • A series of DMMA-based hydrogels for the removal of heavy metals and organic dyes from polluted water. These hydrogels are highly efficient in removing cationic dyes due to electrostatic interaction and hydrogen bonding in the DMMA backbone.
  • Non-toxic luminescent carbon dot/poly(DMMA) nanocomposite via surface-initiated reversible addition-fragmentation chain transfer polymerization.
  • Polymer coating for quartz crystal microbalance(QCM) sensor. The poly(DMMA) gel acts as a sensing material to adsorb Au(III) ions from HCl aqueous solution and it is inactive to most other metal ions and organic compounds.

Features and Benefits

  • It is an appropriate precursor for copolymerization due to its low initiation temperature and high reactivity.
  • Its unique structure forms a 3D network and improves the water retention capacity of hydrogels.
  • It is highly soluble in water.
  • It can easily bind to colloidal particles to enhance the bridging effect which plays a key role in flocculation.

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Eye Dam. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

158.0 °F

flash_point_c

70 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Graft copolymerization of N, N-Dimethylacrylamide to cellulose in homogeneous media using atom transfer radical polymerization for hemocompatibility
Yan L and Wei T
Journal of Biomedical Science and Engineering, 10(1), 37-37 (2008)
Yuriko Matsumura et al.
Polymers, 11(7) (2019-07-20)
In order to clarify the local environment during interpolymer complex formation between poly(carboxylic acids) and poly(acrylamide derivatives) with different N-substitutions, a fluorescence label technique was used. 3-(2-propenyl)-9-(4-N,N-dimethylaminophenyl) phenanthrene (VDP) was used as an intramolecular fluorescence probe. All polymers were synthesized
Copolymerization of N, N-dimethylacrylamide with styrene and butadiene: The first example of polar growing chain end/nonpolar monomer cross-initiation.
Nakhmanovich BI, et al.
Macromolecular Rapid Communications, 22(15), 1243-1248 (2001)
Syed Ragib Safi et al.
Scientific reports, 9(1), 11909-11909 (2019-08-17)
Arsenic contamination of groundwater is a serious concern worldwide. The research gaps in removing arsenic are selectivity, regeneration and effective removal rate at neutral pH levels. In this study, we discussed the reasons of the high arsenic adsorption from groundwater
Koki Sano et al.
Nature communications, 7, 12559-12559 (2016-08-31)
Fluids that contain ordered nanostructures with periodic distances in the visible-wavelength range, anomalously exhibit structural colours that can be rapidly modulated by external stimuli. Indeed, some fish can dynamically change colour by modulating the periodic distance of crystalline guanine sheets

Artículos

The manufacture of monomers for use in ophthalmic applications is driven by the need for higher purity, improved reliability of manufacturing supply, but ultimately by the need for the increased comfort, convenience, and safety of contact lens wearers. Daily wear contact lenses have the potential to fill this need for many customers; however, their widespread use is constrained by higher costs compared to weekly- or monthly-based lenses. New approaches that improve cost structure and result in higher quality raw materials are needed to help make contact lenses more affordable and accelerate growth of the contact lens market.

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