142360

4-Benzylpiperidine

99%

• Sinónimos: Phenyl(4-piperidyl)methane
• Fórmula empírica (notación de Hill): C₁₂H₁₇N
• Número de CAS: 31252-42-3
• Peso molecular: 175.27
• Beilstein/REAXYS Number: 132339
• EC Number: 250-535-0
• MDL number: MFCD00006006
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848521
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 99%
• refractive index: n20/D 1.537 (lit.)
• bp: 279 °C (lit.)
• mp: 6-7 °C (lit.)
• density: 0.997 g/mL at 25 °C (lit.)
• functional group: phenyl
• SMILES string: C1CC(CCN1)Cc2ccccc2
• InChI: 1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2
• InChI key: ABGXADJDTPFFSZ-UHFFFAOYSA-N
• Gene Information: rat ... Htr2a(29595) , Htr2c(25187)

Descripción

General description

4-Benzylpiperidine is dopamine-selective releaser. It is a potential candidate for treatments for cocaine dependence.

Application

4-Benzylpiperidine was used to study the metabolism of 1,3-butadiene and its oxidized metabolites in perfused livers of male B6C3F1 mice and Sprague-Dawley rats.

Reactant for synthesis of:

• Antiproliferatives
• GABA uptake inhibitors
• Pyridines
• Histamine H3 antagonists
• Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer′s and neuronal vascular diseases
• Antiserotoninergic, antiplatelet, hemorheologic, antiarrythmic and antioxidant molecules via nucleophilic substitution

Biochem/physiol Actions

4-Benzylpiperidine inhibits the activity of rat brain monoamine oxidase-A and -B.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 233.6 °F - closed cup
• flash_point_c: 112 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter