Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

125504

Sigma-Aldrich

Cyclopropylamine

98%

Sinónimos:

Aminocyclopropane

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula lineal:
C3H5NH2
Número de CAS:
765-30-0
Peso molecular:
57.09
Beilstein/REAXYS Number:
741858
EC Number:
212-142-2
MDL number:
MFCD00001301
UNSPSC Code:
12352100
PubChem Substance ID:
24847670
NACRES:
NA.22

vapor pressure

4.67 psi ( 20 °C)

Quality Level

200

assay

98%

form

liquid

autoignition temp.

527 °F

refractive index

n20/D 1.420 (lit.)

bp

49-50 °C (lit.)

density

0.824 g/mL at 25 °C (lit.)

SMILES string

NC1CC1

InChI

1S/C3H7N/c4-3-1-2-3/h3H,1-2,4H2

InChI key

HTJDQJBWANPRPF-UHFFFAOYSA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

Application

Cyclopropylamine(CPA) has been used in the synthesis of N-[4-(4-fluoro)phenyl-2-aminothiazol-5-yl]pyrimidin-2-yl-alkylamine derivatives. It has been used in the synthesis of Pt(CPA)2(bismethylthiomethylenepropanedioate) and Pt(CPA)2(bisethylthiomethylenepropanedioate) complexes.

Biochem/physiol Actions

Cyclopropylamine inactivates cytochrome P450 enzymes by a mechanism involving initial one-electron oxidation at nitrogen followed by scission of the cyclopropane ring leading to covalent modification of the enzyme. It is a mechanism-based inhibitor of quinoprotein methylamine dehydrogenase from Paracoccus denitrificans.

For use with

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

33.8 °F - closed cup

flash_point_c

1 °C - closed cup

ppe

Faceshields, Gloves, Goggles

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
STBK5106
STBK0895
STBJ2391
STBH0929
STBG4332V

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Synthesis and Antifungal Activity of 5-[2-(Alkylamino) pyrimidin-4-yl]-4-phenylthiazol-2-cycloalkylamine Derivatives on Phytophthora capsici.
Nam Sw, et al.
J. Korean Chem. Soc., 54(3), 395-402 (2011)
Coordination Mode vs. Anticancer Activity of the Platinum (II) Complexes Involving Sulfur-Containing Ylidenemalonate Ligands.
Sakai N, et al.
Bull. Korean Chem. Soc., 19(12), 1377-1379 (1998)
Dapeng Sun et al.
FEBS letters, 517(1-3), 172-174 (2002-06-14)
Cyclopropylamine is a mechanism-based inhibitor of the quinoprotein methylamine dehydrogenase (MADH) from Paracoccus denitrificans. The resulting inactivation is accompanied by the formation of a covalent cross-link between the alpha and beta subunits of MADH. The results of site-directed mutagenesis studies
Bram Denolf et al.
Organic letters, 9(2), 187-190 (2007-01-16)
Treatment of novel chiral N-sulfinyl alpha-chloro ketimines with Grignard reagents resulted in the synthesis of chiral N-(1-substituted cyclopropyl)-tert-butanesulfinamides in acceptable to good yields and diastereoselectivity via 1,3-dehydrohalogenation and subsequent addition of the Grignard reagent to the intermediate cyclopropylideneamine. Only in
Soda Chanthamath et al.
Organic letters, 15(4), 772-775 (2013-01-31)
The Ru(II)-Pheox-catalyzed asymmetric cyclopropanation of vinylcarbamates with diazoesters resulted in the corresponding cyclopropylamine derivatives in high yield and excellent diastereoselectivity (up to 96:4) and enantioselectivity (up to 99% ee).
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico