Saltar al contenido
Merck

PRKCH

protein kinase C, eta

Sinónimos:
PKC-L, PKCL, PRKCL, nPKC-eta
Especie:
ID UniProtKB:
ID del gen:
  • Human(5583) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq, Jul 2008]
  • Mouse(18755) protein kinase C, eta
  • Rat(81749) protein kinase C, eta
  • cow(518542) protein kinase C, eta
  • sheep(101105574) protein kinase C, eta
  • naked mole-rat(101716769) protein kinase C, eta
  • Domestic Rabbit(100344184) protein kinase C, eta
  • domestic guinea pig(100736222) protein kinase C, eta
  • chicken(423518) protein kinase C, eta
  • Horse(100051560) protein kinase C, eta
  • domestic cat(101082413) protein kinase C, eta
  • dog(490722) protein kinase C, eta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Ácido oleico, ≥99% (GC),
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-PRKCH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Xanthone, 97%,
Especie
mouse
H-7 dihydrochloride, ≥98% (HPLC),
Especie
human
Ácido oleico, ≥99% (GC),
Especie
human
UCN-01, ≥97% (HPLC), powder,
Especie
human
GSK690693, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
PKCη, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Prkch,
Especie
mouse
MISSION® esiRNA, targeting human PRKCH,
Especie
human