PDE4A
phosphodiesterase 4A, cAMP-specific
Sinónimos:
DPDE2, PDE4, PDE46
Especie:
Human PDE4A (5141), Mouse Pde4a (18577), Rat Pde4a (25638), Zebrafish pde4a (572061), chicken PDE4A (769860), dog PDE4A (100683695), domestic cat PDE4A (751107), cow PDE4A (512222), sheep PDE4A (101117505), domestic guinea pig Pde4a (100135594) ...Más
ID UniProtKB:
ID del gen:
- Human(5141) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
- Mouse(18577) phosphodiesterase 4A, cAMP specific
- Rat(25638) phosphodiesterase 4A, cAMP-specific
- Zebrafish(572061) phosphodiesterase 4A, cAMP-specific
- chicken(769860) phosphodiesterase 4A, cAMP-specific
- dog(100683695) phosphodiesterase 4A, cAMP-specific
- domestic cat(751107) phosphodiesterase 4A, cAMP-specific
- cow(512222) phosphodiesterase 4A, cAMP-specific
- sheep(101117505) phosphodiesterase 4A, cAMP-specific
- domestic guinea pig(100135594) phosphodiesterase 4A, cAMP-specific
- naked mole-rat(101717168) phosphodiesterase 4A, cAMP-specific
- Domestic Rabbit(100009247) phosphodiesterase 4A, cAMP-specific
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Small Molecule - Activator
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Small Molecule - Antagonist
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Antibodies
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Reactividad de especies
Aplicación
Anti-PDE4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-PDE4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Small Molecule - Inhibitor
Proteins
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PDE4A1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
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human
PDE4A4B active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥40% (SDS-PAGE),
Especie
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PDE4A10 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE),
Especie
human
