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Merck

GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

Sinónimos:
GAD65
Especie:
ID UniProtKB:
ID del gen:
  • Human(2572) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
  • Mouse(14417) glutamic acid decarboxylase 2
  • Rat(24380) glutamate decarboxylase 2
  • Zebrafish(550403) glutamate decarboxylase 2
  • Thale Cress(842908) glutamate decarboxylase 2
  • chicken(395395) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • domestic cat(101082244) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • cow(512459) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • dog(487107) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • sheep(101106448) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • naked mole-rat(101698166) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • domestic guinea pig(100734029) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GAD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-GAD65 Antibody, clone 3B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-GAD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2736, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse, clone GAD-6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
mammals
Aplicación
immunohistochemistry
western blot
Anti-Glutamic Acid Decarboxylase 65/67 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
feline, human, mouse, pig, rat
Aplicación
immunohistochemistry
microarray

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GAD2,
Especie
human
MISSION® esiRNA, targeting mouse Gad2,
Especie
mouse