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Merck

FLNA

filamin A, alpha

Sinónimos:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Especie:
ID UniProtKB:
ID del gen:
  • Human(2316) Summary: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
  • Mouse(192176) filamin, alpha
  • Rat(293860) filamin A, alpha
  • Zebrafish(562529) filamin A, alpha (actin binding protein 280)
  • cow(281165) filamin A, alpha
  • domestic cat(101082637) filamin A, alpha
  • Zebrafish(100534866) filamin A, alpha
  • dog(481084) filamin A, alpha
  • chicken(395261) filamin A, alpha
  • sheep(101120390) filamin A, alpha
  • Domestic Rabbit(100328754) filamin A, alpha
  • naked mole-rat(101702004) filamin A, alpha
  • domestic guinea pig(100725162) filamin A, alpha

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-FLNA antibody produced in rabbit, Ab3, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-Filamin A Antibody, clone PM6/317 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-FLNA antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Filamin antibody,Mouse monoclonal, clone PM6/317, purified from hybridoma cell culture,
Reactividad de especies
bovine, canine, hamster, human, monkey
Aplicación
immunofluorescence
western blot
Anti-Filamin A antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting human FLNA,
Especie
human