EGFR
epidermal growth factor receptor
Sinónimos:
ERBB, ERBB1, HER1, PIG61, mENA
Especie:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...Más
ID UniProtKB:
ID del gen:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
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ELISA
Referencia del producto
Descripción
Especie
Human EGFR / ErbB1 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Especie
human
Phospho-EGFR (pTyr1068) ELISA Kit, for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates,
Especie
human
Phospho-EGFR (pTyr1068) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1068) and pan-egfr in cell and tissue lysates,
Especie
human
Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-EGFR PE produced in mouse, ,
Reactividad de especies
horse
Aplicación
flow cytometry
Anti-dEGF Receptor, Extracellular Domain antibody, Mouse monoclonal, clone C-273, purified from hybridoma cell culture,
Reactividad de especies
drosophila
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-Epidermal Growth Factor Receptor antibody produced in mouse, clone F4, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
Anti-EGFR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-EGFR (Tyr1068) Antibody, clone 3F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
Especie
human
EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Especie
human
EGFR (T790M L858R) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Especie
human
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Especie
human
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
Especie
human