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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

Sinónimos:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Especie:
ID UniProtKB:
ID del gen:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
western blot
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
western blot
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-phospho-IKK-α/β (pSer180/181) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicación
affinity binding assay
immunohistochemistry

inhibition assay

western blot

Proteins

Referencia del producto
Descripción
Especie
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Chuk,
Especie
mouse
MISSION® esiRNA, targeting human CHUK,
Especie
human