41020AST
Astec® CYCLOBOND™ II Chiral HPLC Column
5 μm particle size, L × I.D. 25 cm × 4.6 mm
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Recommended Products
material
stainless steel column
Quality Level
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-50 °C temperature
172 bar pressure (2500 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
25 cm × 4.6 mm
matrix
silica particle platform
fully porous particle
matrix active group
cyclodextrin, gamma- phase
particle size
5 μm
pore size
100 Å
operating pH
3.5-7
separation technique
chiral
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General description
Consisting of eight glucopyranose units arranged in a truncated cone shape, CYCLOBOND II is an excellent chiral selector for multi-ring structures. It is useful for isomeric compounds based on anthracene, chrysene and pyrene type ring structures. CYCLOBOND II offers good selectivity and stability and is applicable to the polar organic mode of separation. Applications include steroids, porphyrins, FMOC amino acids.
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
- Bonded phase: Underivatized, native γ-cyclodextrin
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
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Series of homologous displacers for preparative chiral displacement chromatographic separations on Cyclobond-II columns
Quintero,Gilberto, et al.
Journal of Chromatography A, 693 (1), 1-5 (1995)
Separation and identification of sulfurized alkylphenols in oil by high-performance liquid chromatography with evaporative light scattering and mass spectrometric detection
Chen, Evan N., Jr., Nero, Vincent P.
Journal of Chromatography A, 549, 247-256 (1991)
A M Abushoffa et al.
Journal of chromatography. A, 700(1-2), 51-58 (1995-05-12)
The methods of separation of the enantiomers of the chiral drug oxamniquine are compared, between HPLC with either cyclodextrins and their related derivatives as chiral selectors in the mobile phase or immobilised in a chiral stationary phase (as Cyclobond I
Optical resolution of flavanones by high-performance liquid chromatography on various chiral stationary phases
Krause, Martin; Galensa, Rodolf
Journal of Chromatography A, 514, 147-159 (1990)
Yasith S Nanayakkara et al.
Journal of chromatography. A, 1305, 94-101 (2013-08-03)
Isochromene derivatives are very important precursors in the natural products industry. Hence the enantiomeric separations of chiral isochromenes are important in the pharmaceutical industry and for organic asymmetric synthesis. Here we report enantiomeric separations of 21 different chiral isochromene derivatives
Related Content
CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.
Chromatograms
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