T5699
m-3M3FBS
>97% (HPLC)
Synonym(s):
2,4,6-Trimethyl-N-(3-trifluoromethyl-phenyl)-benzenesulfonamide, N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide
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About This Item
Empirical Formula (Hill Notation):
C16H16F3NO2S
CAS Number:
Molecular Weight:
343.36
MDL number:
UNSPSC Code:
41106300
PubChem Substance ID:
NACRES:
NA.77
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Assay
>97% (HPLC)
form
powder
color
white
mp
114-114.8 °C (lit.)
solubility
DMSO: >20 mg/mL
SMILES string
Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F
InChI
1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3
InChI key
ZIIUUSVHCHPIQD-UHFFFAOYSA-N
Application
m-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis1. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells2.
Biochem/physiol Actions
First known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms).
Preparation Note
m-3M3FBS is soluble in DMSO at a concentration that is greater than 20 mg/ml.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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