T3396
Tetraglycol
BioXtra
Synonym(s):
Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether
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About This Item
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description
non-ionic
Quality Level
product line
BioXtra
form
liquid (clear)
impurities
<0.5% water (Coulometric)
<5 ppm heavy metal
color
colorless to light yellow
mp
≤ -100 °C
solubility
water: soluble 3420 g/L
density
1.09 g/mL at 25 °C (lit.)
InChI
1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
InChI key
CTPDSKVQLSDPLC-UHFFFAOYSA-N
Application
Tetraglycol has been used:
- to dilute DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) for injecting fertilized chicken eggs for DiI labeling
- to dilute DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) and diO (3,3′-dioctadecyloxacarbocyanine perchlorate) for dye/virus injections
- to dilute poly (lactide-co-glycolide) (PLGA) to prepare PLGA/F127 solution
Used as solvent to dissolve water-insoluble compounds.
Biochem/physiol Actions
Liquid glycofurol can readily transform into gel systems with excellent elasticity due to which, it can be used as a medium to dissolve water-insoluble drugs.
Features and Benefits
Efficient solubilizer for glibenclamide (GBD)
Caution
Do not confuse with tetraethylene glycol, which is also sometimes called tetraglycol.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
275.0 °F - closed cup
Flash Point(C)
135 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Saly Galal et al.
Acta pharmaceutica (Zagreb, Croatia), 53(1), 57-64 (2004-02-11)
The ability of liquid and semi-solid matrix (SSM) filling capsule technology to improve the dissolution rate of glibenclamide (GBD) was investigated. Semiquantitative estimation of GBD solubility in various vehicles was carried out. Tetraglycol was found to be the most efficient
X F Zhang et al.
Materials science & engineering. C, Materials for biological applications, 32(6), 1654-1663 (2012-08-01)
Poly (lactide-co-glycolide) (PLGA) - Pluronic F127 - glass composites have demonstrated excellent potential, from the perspective of controlled mechanical properties and cytocompatibility, for peripheral nerve regeneration. In addition to controlling the mechanical properties and cytotoxicity for such composite devices, the
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