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Key Documents

SML0255

Sigma-Aldrich

4-DAMP

≥98% (HPLC)

Synonym(s):

1,1-Dimethyl-4-diphenylacetoxypiperidinium iodide, 4-DAMP methiodide, 4-Diphenylacetoxy-N-methylpiperidine methiodide, 4-[(Diphenylacetyl)oxy]-1,1-dimethyl-piperidinium iodide

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About This Item

Empirical Formula (Hill Notation):
C21H26INO2
CAS Number:
Molecular Weight:
451.34
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: ≥15 mg/mL

storage temp.

room temp

SMILES string

[I-].C[N+]1(C)CCC(CC1)OC(=O)C(c2ccccc2)c3ccccc3

InChI

1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1

InChI key

WWJHRSCUAQPFQO-UHFFFAOYSA-M

Biochem/physiol Actions

4-DAMP is a M3 preferring cholinergic receptor antagonist.
4-DAMP is a muscarinic receptor antagonist; M3 preferring cholinergic receptor antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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