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SAB4300235

Sigma-Aldrich

Anti-phospho-PRKCD (pSer645) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-40299 antibody produced in rabbit, Anti-MGC49908 antibody produced in rabbit, Anti-PKCD antibody produced in rabbit, Anti-nPKC-delta antibody produced in rabbit, Anti-protein kinase C, delta antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~78 kDa

species reactivity

human, rat

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(R-L-SP-Y-S)

NCBI accession no.

NP_006245.2

UniProt accession no.

Q05655

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer645)

Gene Information

human ... PRKCD(5580)

Immunogen

Peptide sequence around phosphorylation site of serine 645 (R-L-S(p)-Y-S), according to the protein PRKCD.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
951411296

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