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Key Documents

S5571

Sigma-Aldrich

β-Synuclein histidine-tagged human

N-terminal, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder

Synonym(s):

SNCB

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About This Item

MDL number:
UNSPSC Code:
12352202

recombinant

expressed in E. coli

Quality Level

Assay

≥90% (SDS-PAGE)

form

lyophilized powder

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... SNCB(6620)

Biochem/physiol Actions

β-synuclein is an acidic, neuronal protein considered to be a non-amyloidogenic homolog of α-synuclein. It has been postulated that β-synuclein could act as a physiological inhibitor of α-synuclein aggregation and thus protect the central nervous system from the neurotoxic effects of α-synuclein.

Reconstitution

Reconstitute with 0.5 mL water (~1 mg/mL). Store in working aliquots at −20 °C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Makoto Hashimoto et al.
The Journal of biological chemistry, 279(22), 23622-23629 (2004-03-18)
Recent studies have shown that the neurodegenerative process in disorders with Lewy body formation, such as Parkinson's disease and dementia with Lewy bodies, is associated with alpha-synuclein accumulation and that beta-synuclein might protect the central nervous system from the neurotoxic

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