O7139
Monoclonal Anti-Oligodendrocyte Marker O4 antibody produced in mouse
clone O4, purified immunoglobulin, lyophilized powder
Synonym(s):
Oligodendrocyte Marker O4 Antibody
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About This Item
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biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
O4, monoclonal
form
lyophilized powder
species reactivity
mouse, rat, chicken, human
technique(s)
flow cytometry: 0.25 μg/106 cells (rate differentiated cortical stem cells)
immunocytochemistry: 1-10 μg/mL
isotype
IgM
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... OMG(4974)
General description
Monoclonal anti-oligodendrocyte marker O4 was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with white matter of the corpus callosum from bovine brain. Oligodendrocytes are myelinating cells in the central nervous system (CNS) that form the myelin sheath of axons to support rapid nerve conduction.
Immunogen
white matter of corpus callosum from bovine brain.
Application
Monoclonal anti-oligodendrocyte marker O4 antibody produced in mouse has been used in immunocytochemistry and immunofluorescence.
Biochem/physiol Actions
Oligodendrocyte marker O4 functions as a development marker of oligodendrocytes. The monoclonal anti-oligodendrocyte marker O4 antibody has been used to describe a biologically distinct stage of the oligodendroglial lineage in-vitro.†
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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SDF-1a Secreted by Human CD133-Derived Multipotent Stromal Cells Promotes Neural Progenitor Cell Survival Through CXCR7
Stem Cells and Development (2011)
An efficient and economical culture approach for the enrichment of purified oligodendrocyte progenitor cells.
Journal of Neuroscience Methods, 209, 241-249 (2012)
M2 microglia promotes neurogenesis and oligodendrogenesis from neural stem/progenitor cells via the PPAR? signaling pathway
Oncotarget (2017)
Oligodendrocytes: biology and pathology
Acta Neuropathologica, 119, 37-53 (2010)
Neuroglial Cells in Long-Term Primary Cultures from the Gilthead Seabream (Sparus Aurata L.): New Functional In Vitro Model from Bony Fish Brain
Italian Journal of Animal Science, 12 (2013)
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