MAK132
Sulfate Assay Kit
sufficient for 200 tests (turbidimetric)
Synonym(s):
Sulfate Determination Kit
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
Recommended Products
usage
sufficient for 200 tests (turbidimetric)
detection method
turbidimetric
relevant disease(s)
genitourinary disorders
storage temp.
room temp
General description
Inorganic sulfate is one of the most abundant anions in mammalian plasma. Sulfate plays important physiological roles in activating and detoxifying xenobiotics, steroids, neurotransmitters, and bile acids. Sulfate is needed for the biosynthesis of cerebroside sulfate, glycosaminoglycans, and heparin sulfate. Undersulfation of cartilage proteoglycans has been associated with human inherited osteochondro-dysplasia disorders. In mammals, sulfate homeostasis is regulated by the kidney. The majority of filtered sulfate is absorbed in the proximal tubules and only 5-20% of the filtered load is excreted into the urine.
Application
Sulfate Assay Kit has been used to determine the concentration of sulfate.
Features and Benefits
Compatible with high-throughput handling systems. Can be adapted for use with cuvettes.
Suitability
Suitable for the detection of sulfate in biological fluids such as serum and urine.
Principle
The kit employs an improved method utilizes the quantitative formation of insoluble barium sulfate in polyethylene glycol. The turbidity measured at 600 nm is proportional to sulfate level in the sample.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
8A - Combustible corrosive hazardous materials
Certificates of Analysis (COA)
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Physiological Roles and Regulation of Mammalian Sulfate Transporters.
Daniel M.
Physiological Reviews, 81(4) (2001)
Partial deletion of the sulfate transporter SLC13A1 is associated with an osteochondrodysplasia in the Miniature Poodle breed.
Neff M W, et al.
PLoS ONE, 7(12), e51917-e51917 (2012)
Esters production via carboxylates from anaerobic paper mill wastewater treatment.
Carlos I C R, et al.
Bioresource Technology, 237, 186-192 (2017)
Molecular aspects of renal tubular handling and regulation of inorganic sulfate.
Beck L and Caroline S
Kidney International, 59(3), 835-845 (2001)
Transcriptional regulation of the sodium-sulfate cotransporter NaSi-1 gene.
Dawson P A and Daniel M
Cell Biochemistry and Biophysics, 36(2-3), 175-182 (2002)
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