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M0944

Sigma-Aldrich

Anti-Msx1 antibody produced in rabbit

affinity isolated antibody, ammonium sulfate suspension

Synonym(s):

Anti-HOX7, Anti-msh homeo box homolog 1 (Drosophila)

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About This Item

MDL number:
MFCD07370403
UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

ammonium sulfate suspension

mol wt

antigen 30.9 kDa

species reactivity

human, rodent

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

P28360

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MSX1(4487)
mouse ... Msx1(17701)
rat ... Msx1(81710)

Immunogen

synthetic peptide corresponding to human Msx1 (amino acids 42-52), conjugated to BSA.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)

Target description

Msx1 encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Minglian Zhao et al.
Molecular and cellular biology, 33(16), 3099-3112 (2013-06-12)
Improving the knowledge of disease-causing genes is a unique challenge in human health. Although it is known that genes causing similar diseases tend to lie close to one another in a network of protein-protein or functional interactions, the identification of
F Wehrhan et al.
Oral diseases, 17(4), 433-442 (2011-03-04)
Bone-destructive disease treatments include bisphosphonates and antibodies against receptor activator for nuclear factor κB ligand (aRANKL). Osteonecrosis of the jaw (ONJ) is a side-effect. Aetiopathology models failed to explain their restriction to the jaw. The osteoproliferative transcription factor Msx-1 is
Marcos S Simões-Costa et al.
PLoS genetics, 8(12), e1003142-e1003142 (2013-01-04)
The critical stem cell transcription factor FoxD3 is expressed by the premigratory and migrating neural crest, an embryonic stem cell population that forms diverse derivatives. Despite its important role in development and stem cell biology, little is known about what
Irfan Saadi et al.
Development (Cambridge, England), 140(13), 2697-2702 (2013-05-31)
Bmp4 expression is tightly regulated during embryonic tooth development, with early expression in the dental epithelial placode leading to later expression in the dental mesenchyme. Msx1 is among several transcription factors that are induced by epithelial Bmp4 and that, in
Marcos Simões-Costa et al.
Developmental cell, 34(5), 544-554 (2015-08-11)
Neural crest cells are induced at the neural plate border by the combined action of transcription factors and signaling molecules. Here, we show that Axud1, a downstream effector of Wnt signaling, represents a critical missing link that integrates signaling and
View All Related Papers

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