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EHU009211

Sigma-Aldrich

MISSION® esiRNA

targeting human FAM96B

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

ATGCCAACCCCCTCATCTACCAGCGCTCTGGGGAGCGGCCTGTGACGGCAGGCGAGGAGGACGAGCAGGTTCCCGACAGCATCGACGCACGCGAGATCTTCGATATCCGCCGCTGCTGGGCGCGGGCGGCACATCCACTGACGCTAGAGGAGTTGAACGTAGTAGAGCAGGTGCGGGTTCAGGTTAGCGACCCCGAGAGTACAGTGGCTGTGGCTTTCACACCAACCATTCCGCACTGCAGCATGGCCACCCTTATTGGTCTGTCCATCAAGGTCAAGCTTCTGCGCTCCCTTCCTCAGCGTTTCAAGATGGACGTGCACATTACTCCGGGGACCCATGCCTCAGAGCATGCAGTGAACAAGCAACTTGCAGATAAGGAGCGGGTGGCAGCTGCCCTGGAGAACACCCACCTCTTGGAGGTTGTGAATCAGTGC

Ensembl | human accession no.

ENSG00000166595

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... FAM96B(51647) , FAM96B(51647)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Adarsh K Mayank et al.
Molecular cell, 75(2), 382-393 (2019-06-24)
The iron-sensing protein FBXL5 is the substrate adaptor for a SKP1-CUL1-RBX1 E3 ubiquitin ligase complex that regulates the degradation of iron regulatory proteins (IRPs). Here, we describe a mechanism of FBXL5 regulation involving its interaction with the cytosolic Fe-S cluster

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