D4010
2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate
≥96% (HPLC)
Synonym(s):
2′-deoxy-, 5′-triphosphate sodium salt, Guanosine, dGTP sodium salt hydrate
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About This Item
Empirical Formula (Hill Notation):
C10H16N5O13P3 · xNa+ · yH2O
CAS Number:
Molecular Weight:
507.18 (anhydrous free acid basis)
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
biological source
synthetic (organic)
Assay
≥96% (HPLC)
form
powder
shipped in
dry ice
storage temp.
−20°C
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Application
2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate has been used:
- as a component in a polymerase chain reaction (PCR) mixture for PCR product formation using AM-toxin primers
- as an internal standard to improve the analytical performance of capillary electrophoresis (CE) analysis for the evaluation of the cleanup process
- as a putative substrate in in vitro enzyme activity assay to incubate with nudix hydrolase 15 (NUDT15) protein for the evaluation of putative NUDT15 inhibitors
Biochem/physiol Actions
Deoxyguanosine 5′-triphosphate (dGTP), a purine deoxynucleotide, is a substrate of DNA polymerase(s) and reverse transcriptases. dGTP is useful to study the distribution, specificity, and kinetics of various nucleoside-triphosphatases (NTPase) and ribonucleotide reductases.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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