C9357

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)

≥96% (HPLC), suitable for western blotting and enzyme immunoassays

• Synonym(s): XJ735
• Empirical Formula (Hill Notation): C₂₃H₃₂N₈O₇
• CAS Number: 153381-95-4
• Molecular Weight: 532.55
• MDL number: MFCD11046000
• UNSPSC Code: 12352209
• PubChem Substance ID: 329775202
• NACRES: NA.26

Properties

• product name: Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl), ≥96% (HPLC)
• Quality Level: 200
• Assay: ≥96% (HPLC)
• form: powder
• technique(s): enzyme immunoassay: suitable; western blot: suitable
• color: white
• UniProt accession no.: P01303
• storage temp.: −20°C
• SMILES string: C[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)c2
• InChI: 1S/C23H32N8O7/c1-12-19(35)31-15(6-3-7-26-23(24)25)21(37)28-11-17(32)30-16(9-18(33)34)22(38)27-10-13-4-2-5-14(8-13)20(36)29-12/h2,4-5,8,12,15-16H,3,6-7,9-11H2,1H3,(H,27,38)(H,28,37)(H,29,36)(H,30,32)(H,31,35)(H,33,34)(H4,24,25,26)/t12-,15-,16-/m0/s1
• InChI key: HRASXYOWQQTBAQ-RCBQFDQVSA-N
• Gene Information: human ... NPY(4852)

Description

Amino Acid Sequence

Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl

Biochem/physiol Actions

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes.

Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves