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85541

Sigma-Aldrich

L-(−)-Sorbose

for biotechnological purposes, ≥98.0% (sum of enantiomers, HPLC)

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
87-79-6
Molecular Weight:
180.16
Beilstein:
1724554
EC Number:
201-771-8
MDL number:
MFCD00151097
UNSPSC Code:
12352201
PubChem Substance ID:
57653051
NACRES:
NA.25

grade

for biotechnological purposes

Assay

≥98.0% (sum of enantiomers, HPLC)

form

solid

optical activity

[α]20/D −43±2°, c = 5% in H2O

color

colorless

mp

163-165 °C

solubility

H2O: 0.1 g/mL, clear, colorless to very faintly yellow

SMILES string

OC[C@H](O)[C@@H](O)[C@H](O)C(=O)CO

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5+,6+/m0/s1

InChI key

BJHIKXHVCXFQLS-OTWZMJIISA-N

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Application

L-Sorbose is used as a starting reagent for the commercial biosynthesis of ascorbic acid (vitamin C).

Biochem/physiol Actions

The L enatiomer of sorbose, a ketohexose monosaccharide.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Journal of biotechnology, 300, 55-62 (2019-05-18)
6-(N-hydroxyethyl) amino-6-deoxy-l-sorbofuranose (6NSL) is the direct precursor of miglitol for diabetes therapy. The regio- and stereo-selective dehydrogenation offered by the membrane-bound d-sorbitol dehydrogenase (mSLDH) from Gluconobacter oxydans provides an elegant enzymatic method for 6NSL production. In this study, two subunits
Cai-Hui Pan et al.
Journal of industrial microbiology & biotechnology, 44(7), 1031-1040 (2017-03-12)
Defect in the amino acid biosynthetic pathways of Ketogulonicigenium vulgare, the producing strain for 2-keto-L-gulonic acid (2-KGA), is the key reason for its poor growth and low productivity. In this study, five different strains were firstly reconstructed by expressing absent
Weizhu Zeng et al.
Bioresource technology, 318, 124069-124069 (2020-09-12)
The 2-keto-L-gulonic acid (2-KLG) is the direct precursor for industrial vitamin C production. The main biosynthetic method for 2-KLG production is the classical two-step fermentation route. However, disadvantages of this method are emerging, including high consumption of energy, difficulties in
Yue Chen et al.
Frontiers in bioengineering and biotechnology, 7, 385-385 (2020-01-11)
High-throughput screening is a powerful tool for discovering strains in the natural environment that may be suitable for target production. Herein, a novel enzyme-based high-throughput screening method was developed for rapid screening of strains overproducing 2-keto-L-gulonic acid (2-KLG). The screening
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