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PHR1202

Supelco

Caprylic Acid (Octanoic Acid)

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Octanoic acid, Caprylic acid, OA, OcAc, Acid C8

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About This Item

Linear Formula:
CH3(CH2)6COOH
CAS Number:
Molecular Weight:
144.21
Beilstein:
1747180
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. C0426000
traceable to USP 1091040

vapor density

5 (vs air)

vapor pressure

1 mmHg ( 78 °C)

API family

caprylic acid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.428 (lit.)

bp

237 °C (lit.)

mp

15-17 °C (lit.)

density

0.91 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCCCCC(O)=O

InChI

1S/C8H16O2/c1-2-3-4-5-6-7-8(9)10/h2-7H2,1H3,(H,9,10)

InChI key

WWZKQHOCKIZLMA-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Caprylic Acid (Octanoic Acid) may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3467 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

>230.0 °F - closed cup

Flash Point(C)

> 110 °C - closed cup


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Profiling of medium chain glycerides used in pharmaceutical formulation development by reversed-phase HPLC
Fliszar KA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(4), 896-900 (2006)
Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situ densitometric analysis
Sek L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 25(3-4), 651-661 (2001)
Development of a liquid chromatographic method for ear drops containing neomycin sulphate, polymyxin B sulphate and dexamethasone sodium phosphate.
Pendela M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 751-757 (2004)
Phospholipid hydrolysis in a pharmaceutical emulsion assessed by physicochemical parameters and a new analytical method.
Rabinovich-Guilatt L, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 61(1-2), 69-76 (2005)
Joshua A Jackman et al.
Journal of animal science and biotechnology, 11(1), 114-114 (2020-12-10)
The ongoing African swine fever virus (ASFv) epidemic has had a major impact on pig production globally and biosecurity efforts to curb ASFv infectivity and transmission are a high priority. It has been recently identified that feed and feed ingredients

Protocols

HPLC Analysis of Cresols and Phenol on Astec® CYCLOBOND® I 2000

In this study, SPME was used for the analysis of free fatty acids in Parmesan cheese using a 65 μm Carbowax/divinylbenzene (DVB) SPME fiber. Headspace extraction of the cheese sample was conducted at 65 °C for 15 minutes and analyzed by GC with FID detection. SPME is ideal for analyzing the volatiles associated with solid food samples. The phase chemistry of the Nukol GC column provides excellent peak shape of acidic compounds.

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