NIST2972A

25-Hydroxyvitamin D calibration solutions

NIST^® SRM^® 2972a

• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 100
• packaging: pkg of 20 x 1.2 mL
• manufacturer/tradename: NIST^®
• application(s): pharmaceutical (small molecule)
• format: matrix material

Description

General description

This Standard Reference Material (SRM) is intended primarily for use in calibration of instruments and techniques used for the determination of these vitamin D metabolites. A unit consists of twenty, two-milliliter ampoules, of four separate ethanolic solutions of vitamin D metabolites, five ampoules of each solution. Each two-milliliter ampoule contains approximately 1.2 mL of solution. The four separate ethanolic solutions of vitamin D metabolites are described below. For more information, please refer to theSDS andCOA.

25-Hydroxyvitamin D3 Calibrant in Ethanol Level 1 [25(OH)D3 in Ethanol Level 1]25-Hydroxyvitamin D3 Calibrant in Ethanol Level 2 [25(OH)D3 in Ethanol Level 2] 25-Hydroxyvitamin D2 Calibrant in Ethanol [25(OH)D2 in Ethanol]3-Epi-25-hydroxyvitamin D3 Calibrant in Ethanol [3-epi-25(OH)D3 in Ethanol]

SRM 2972A_cert

SRM 2972A_SDS

Application

• Advanced Calibration for Vitamin D Analysis: The use of 25-Hydroxyvitamin D calibration solutions is pivotal in the development of a candidate reference method for the determination of vitamin D levels from dried blood spot samples. This method offers significant advantages in clinical settings, providing reliable and accurate assessment of vitamin D status which is crucial for diagnosing and managing conditions related to vitamin D deficiency. The research conducted by Zakaria et al. (2020) introduces a standardized approach that enhances the consistency of vitamin D measurements across various laboratories, ensuring high-quality diagnostic information (Zakaria et al., 2020).

Other Notes

Example analytes are listed below as a reference. Please download a current certificate at nist.gov/SRM for current analytes and certified values.
Vitamin D Metabolites: 25-Hydroxyvitamin D₃ (Level 1), 25-Hydroxyvitamin D₃ (Level 2), 25-Hydroxyvitamin D₂, 3-Epi-25-hydroxyvitamin D₃.

Legal Information

NIST is a registered trademark of National Institute of Standards and Technology

SRM is a registered trademark of National Institute of Standards and Technology

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225 - H319
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 55.4 °F
• Flash Point(C): 13 °C