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29221

Sigma-Aldrich

Ethanol (denatured)

tested according to Ph. Eur., USP/NF

Synonym(s):

Ethanolum (96 per centum), Ethyl alcohol

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About This Item

Linear Formula:
CH3CH2OH
CAS Number:
Molecular Weight:
46.07
Beilstein:
1718733
EC Number:
MDL number:
UNSPSC Code:
12191601
PubChem Substance ID:
NACRES:
NA.55

product name

Ethanol, tested according to Ph. Eur.

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

vapor density

1.59 (vs air)

vapor pressure

44.6 mmHg ( 20 °C)

form

liquid

autoignition temp.

683 °F

expl. lim.

19 %, 60 °F

refractive index

n20/D 1.3600 (lit.)

bp

78 °C (lit.)

mp

−114 °C (lit.)

solubility

H2O: soluble

density

0.789 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCO

InChI

1S/C2H6O/c1-2-3/h3H,2H2,1H3

InChI key

LFQSCWFLJHTTHZ-UHFFFAOYSA-N

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Application

Ethanol has been used in indirect immunofluorescence for washing the mouse tissues section and then mounted in elvanol for visualizing with a BX60 photomicroscope. It has also been used for thymocyte preparation.

Biochem/physiol Actions

Ethanol provides controlled pH, temperature and ionic strength for protein separation. It blocks the ion current induced by the glutamate receptor agonist N-methyl-D-aspartate (NMDA) in hippocampal neurons.

Footnote

1Distribution and use of ethyl alcohol in Switzerland require a license from the Swiss Federal Alcohol Administration

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

55.4 °F

Flash Point(C)

13 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M G Mahoney et al.
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Patients with pemphigus foliaceus (PF) have blisters on skin, but not mucous membranes, whereas patients with pemphigus vulgaris (PV) develop blisters on mucous membranes and/or skin. PF and PV blisters are due to loss of keratinocyte cell-cell adhesion in the
D M Lovinger et al.
Science (New York, N.Y.), 243(4899), 1721-1724 (1989-03-31)
The ion current induced by the glutamate receptor agonist N-methyl-D-aspartate (NMDA) in voltage-clamped hippocampal neurons was inhibited by ethanol (EtOH). Inhibition increased in a concentration-dependent manner over the range 5 to 50 mM, a range that also produces intoxication. The
Y Gavrieli et al.
The Journal of cell biology, 119(3), 493-501 (1992-11-01)
Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown
S Enocksson et al.
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(8), 2017-2028 (2014-03-04)
Mesolimbic dopamine (DA) controls drug- and alcohol-seeking behavior, but the role of specific DA receptor subtypes is unclear. We tested the hypothesis that D3R gene deletion or the D3R pharmacological blockade inhibits ethanol preference in mice. D3R-deficient mice (D3R(-/-)) and

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