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MAB379

Sigma-Aldrich

Anti-Glutamate Receptor 5, 6, 7 Antibody, clone 4F5

ascites fluid, clone 4F5, Chemicon®

Synonym(s):

GluR5/6/7

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4F5, monoclonal

species reactivity

rat, human, monkey

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
radioimmunoassay: suitable

isotype

IgM

NCBI accession no.

NM_000830.3

UniProt accession no.

P22756
P39086
Q38PU4

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRIK1(2897)

Specificity

Recognizes an epitope common to Glutamate Receptors 5, 6 and 7. No reactivity seen to GluR1, GluR2, GluR3 or GluR4.

Immunogen

Recombinant fusion protein TrpE-GluR5

Application

Anti-Glutamate Receptor 5, 6, 7 Antibody, clone 4F5 detects level of Glutamate Receptor 5 & has been published & validated for use in ELISA, IC, IH, RIA.
Immunohistochemistry on 4% paraformaldehyde fixed tissue:1:1,000-1:2,000 Immunocytochemistry

ELISA

RIA

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Physical form

Ascites. Liquid. Contains no preservative.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Toxic effects of domoic acid in the seabream Sparus aurata.
Nogueira, I; Lobo-da-Cunha, A; Afonso, A; Rivera, S; Azevedo, J; Monteiro, R; Cervantes et al.
Marine drugs null
Absence of neurotoxic effects in leopard sharks, Triakis semifasciata, following domoic acid exposure.
P Schaffer, C Reeves, D R Casper, C R Davis
Toxicon null
Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7
Huntley, G W, et al
The Journal of Neuroscience, 13, 2965-2981 (1993)
Duygu Gok Yurtseven et al.
Brain sciences, 10(9) (2020-09-17)
Nesfatin-1, identified as an anorexigenic peptide, regulates the energy metabolism by suppressing food intake. The majority of nesfatin-1-synthesizing neurons are concentrated in various hypothalamic nuclei, especially in the supraoptic (SON), arcuate (ARC) and paraventricular nuclei (PVN). We tested the hypothesis
David R Micklem et al.
BMC biotechnology, 14, 57-57 (2014-06-24)
The dose-response relationship is a fundamental pharmacological parameter necessary to determine therapeutic thresholds. Epi-allelic hypomorphic analysis using RNA interference (RNAi) can similarly correlate target gene dosage with cellular phenotypes. This however requires a set of RNAi triggers empirically determined to

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